MIBETA, MIBETA SR

(Propranolol 10 mg & 20 mg) Tablet (Propanolol SR 40mg / SR 80mg) Tablet

Neurology

MIBETA, MIBETA SR

(Propranolol 10 mg & 20 mg) Tablet (Propanolol SR 40mg / SR 80mg) Tablet

Neurology

Indications

Mibeta is indicated for the migraine prophylaxis & in Portal Hypertension in liver cirrhotic patients.

How it works

Mibeta contains Propranolol, Non-Selective β-blockers used to reduce the severity and frequency of migraine headaches.

Indications

Mibeta is indicated for the migraine prophylaxis & in Portal Hypertension in liver cirrhotic patients.

Dosage

Migrane Prophylaxsis: Mibeta SR 40 / 80 mg once a day.
Portal hypertension: Mibeta SR 40 / 80 mg initially, 40 mg bid increased at wkly intervals up to 160 mg bid. As extended release cap: 80 mg once daily, may be increased to 160 mg once daily. Max: 320 mg once daily.
Hepatic impairment: Severe: 20 mg tid. As extended release cap: 80 mg once daily or 160 mg every other day.

Side Effects

Propranolol: Cold extremities, insomnia, fatigue, dizziness, nausea, constipation or diarrhoea, vomiting, anorexia, stomach discomfort, impotence. Weakness, paraesthesia, wheezing, pharyngitis, bronchospasm. CNS disturbances at higher doses and mood alterations. Depression, confusion, cognitive dysfunction, emotional lability, fatigue, hallucinations.
Pregnancy & Lactation – Not recommended in patients receiving propranolol therapy

Contraindication

Sinus bradycardia, cardiogenic shock, sick sinus syndrome, Raynaud’s syndrome, 2nd and 3rd degree heart block, overt CHF, bronchial asthma, COPD, untreated phaeochromocytoma, Prinzmetal’s angina; severe peripheral arterial disease, metabolic acidosis. Concomitant use w/ thioridazine.

Technical information

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Neurology

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