CLOTAS MD-Clonazepam 0.25/0.5/1/2mg Mouth Dissolving Tablet
CLOTAS PLUS-Clonazepam 0.5mg +Propranolol 20mg tablet
CLOTAS-E -Clonazepam 0.5mg +Escitalopram 10mg tablet
CLOTAS-EH-Clonazepam 0.25mg +Escitalopram 5mg tablet
CLOTAS MD-Clonazepam 0.25/0.5/1/2mg Mouth Dissolving Tablet
CLOTAS PLUS-Clonazepam 0.5mg +Propranolol 20mg tablet
CLOTAS-E -Clonazepam 0.5mg +Escitalopram 10mg tablet
CLOTAS-EH-Clonazepam 0.25mg +Escitalopram 5mg tablet
Psychosomatic Disorders Associated With Anxiety
Mild Anxiodepressive Disorder
How it works
Clonazepam is a benzodiazepine drug having anxiolytic, anticonvulsant, muscle relaxant, amnestic, sedative, and hypnotic properties. Clonazepam reduces the nerve transmission in the motor cortex which suppresses the spike and wave discharge in absence seizures. Its mechanism is believed to be related to its ability to enhance the activity of GABA. Clinically, it improves focal epilepsy and generalised seizures.
Propranolol is a nonselective beta blocker; that is, it blocks the action of epinephrine and norepinephrine on both β1- and β2-adrenergic receptors. It has little intrinsic sympathomimetic activity, but has strong membrane stabilizing activity (only at high blood concentrations, e.g. overdosage). Propranolol has inhibitory effects on thenorepinephrine transporter and/or stimulates norepinephrine release (the concentration of norepinephrine is increased in the synapse).
Escitalopram is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is approved by the U.S. Food and Drug Administration(FDA) for the treatment of adults and children over 12 years of age with major depressive disorder (MDD) and generalized anxiety disorder (GAD).
Indications
Psychosomatic Disorders Associated With Anxiety
Mild Anxiodepressive Disorder
Dosage
Tab Once in a Day/Twice in a day
Side Effects
Drowsiness or sedation, fatigue, muscular hypotonia, behavioural disturbances including aggressiveness, agitation, hyperkinesis and irritability; coordination disturbances, dizziness, vertigo, anorexia, visual disturbances.
Contraindication
Patient w/o acute angle closure glaucoma, acute pulmonary insufficiency, severe resp insufficiency, myasthenia gravis, sleep apnoea syndrome