LAM-ET

(ETIZOLAM 0.25/0.5MG Mouth Dissolving Tablet)

Neurology

LAM-ET

(ETIZOLAM 0.25/0.5MG Mouth Dissolving Tablet)

Neurology

Indications

Generalized anxiety disorder
Panic Anxiety Disorder

How it works

ETIZOLAM in LAM-ET molecule differs from a benzodiazepine in that the benzene ring has been replaced by a  thiophene ring, making the drug a thienodiazepine.It possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It acts by binding to the GABA (Gamma amino butyric acid) receptors. The binding of benzodiazepines to the GABA-A receptor increases the affinity of gamma amino butyric acid (GABA) and its receptor, thereby increasing the opening frequency of GABA-A receptor. As a consequence of this, benzodiazepines potentiate GABA-ergic neurotransmission, resulting in anxiolytic (anti-anxiety), anticonvulsant, muscle relaxant, sedative and hypnotic effects.

Indications

Generalized anxiety disorder
Panic Anxiety Disorder

Dosage

0.5-1 mg /day

Side Effects

Drowsiness, sedation, muscle weakness and ataxia. Less frequently, vertigo, headache, confusion, depression, slurred speech or dysarthria, changes in libido, tremor, visual disturbances, urinary retention or incontinence, GI disturbances, changes in salivation and amnesia.

Contraindication

Acute narrow-angle glaucoma; myasthenia gravis; resp depression; coma; acute pulmonary insufficiency; sleep apnoea syndrome; severe hepatic impairment. Chronic psychosis. Phobic or obsessional states; may precipitate suicide or aggressive behavior, not to be used alone to treat depression or anxiety associated with depression. Porphyria. Pregnancy and lactation. Neonates.

Technical information

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Neurology

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