Hypertension
Hypertension associated with palpitation
Hypertension associated with edema
How it works
Olmesartan is an angiotensin II receptor antagonist & Hydrochlorothiazide is a thiazide diuretic used for the treatment of high blood pressure.
Indications
Hypertension
Hypertension associated with palpitation
Hypertension associated with edema
Dosage
1 tab. O.D
Side Effects
Olmesartan:
Dizziness, itching, skin rash, difficulty in breathing or swallowing.
Hydrochlorothiazide
Volume depletion and electrolyte imbalance (especially hyperkalaemia); dry mouth, thirst; lethargy, drowsiness; muscle pain and cramps; rashes, photosensitivity, thrombocytopenia, jaundice, pancreatitis; fatigue, weakness; may precipitate an attack of gout; impotence; hyperglycaemia; anorexia, nausea, vomiting, constipation, diarrhoea; sialdenitis; raised urinary calcium concentration; headache, dizziness; back pain, myalgia; first-dose hypotension; angiodema; neutropenia; GI disturbances; transient elevation of liver enzymes; taste disturbances, cough; exacerbation or activation of systemic lupus erythematous; palpitations; xanthopsia; leucopenia, agranulocytosis, aplastic anaemia; necrotising angiitis; glucosuria; renal dysfunction, interstitial nephritis, renal failure; migraine; hyponatraemia; UTI; chest pain; gastritis, wt gain, dyspepsia, abdominal pain; bronchitis, upper respiratory infection, nasal congestion, sinusitis; rise in cholesterol and/or triglycerides.
Potentially Fatal: Hypersensitivity reactions; hemolytic anaemia; toxic epidermal necrolysis.
Contraindication
Patients who are hypersensitive to this drug or to any ingredient in the formulation.
Concomitant use of angiotensin receptor antagonists (ARBs) including olmesartan with aliskiren-containing drugs in patients with diabetes mellitus (type 1 or type 2) or moderate to severe renal impairment (GFR <60mL/min/1.73 m2)