Non Malignant Peptic Ulcer
Duodenal Ulcer, Gastric ulcer
Stress Ulcer Prophylaxis
How it works
The combination ensures prolonged coating of ulcer + anesthetic action to mucous membranes, thus promotes quick healing and relief from pain.
Sucralfate
It’s a unique oral drug that is used for treating ulcers of the upper gastrointestinal tract. Chemically, it is a complex of the disaccharide sugar, sucrose, combined with sulfate and aluminum. It is minimally absorbed into the body, and its actions are entirely on the lining of the stomach and duodenum. Although its mechanism of action is not entirely understood, the following actions are thought to be important for its beneficial effects:
Sucralfate binds to the surface of ulcers (attaching to exposed proteins) and coats the ulcer, thus protecting the ulcer surface to some extent from further injury by acid and pepsin;
Sucralfate directly inhibits pepsin (an enzyme that breaks apart proteins) in the presence of stomach acid;
Sucralfate binds bile salts coming from the liver via the bile thus protecting the stomach lining from injury caused by the bile acids;
Sucralfate may increase prostaglandin production and prostaglandins are known to protect the lining of the stomach.
Oxetacaine
It is a local anaesthetic of the amide type.
It produces a reversible loss of sensation by preventing or diminishing the conduction of sensory nerve impulses near the site of its application.
It decreases the permeability of the nerve cell membrane to sodium ions by membrane stabilising effect.
Relieves pain, bloating, discomfort and fullness
Indications
Non Malignant Peptic Ulcer
Duodenal Ulcer, Gastric ulcer
Stress Ulcer Prophylaxis
Dosage
Shake well before use. Give 10-15ml one hour before each meal and at bedtime.
Side Effects
Constipation, diarrhea, nausea, dizziness, dry mouth, GI disturbances, rash, pruritis, headache, vertigo, back pain & drowsiness, Nervousness, Blurred vision.
Contraindication
Contraindicated in patients with proven allergy to any ingredient