ITORAX- ITOPRIDE 50 MG TABLET
ITORAX- OD – ITOPRIDE 150MG SR
ITORAX-RB- ITOPRIDE (SR) 150MG +RABEPRAZOLE 20MG CAPSULE
ITORAX- ITOPRIDE 50 MG TABLET
ITORAX- OD – ITOPRIDE 150MG SR
ITORAX-RB- ITOPRIDE (SR) 150MG +RABEPRAZOLE 20MG CAPSULE
Chronic gastritis
GERD
Non ulcer dyspepsia
How it works
Itopride is a prokinetic benzamide derivative unlike metoclopramide or domperidone. These drugs inhibit dopamine and have a gastrokinetic effect. Itopride increases acetylcholine concentrations by inhibiting dopamine D2 receptors and acetylcholinesterase. Higher acetylcholine increases GI peristalsis, increases the lower esophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying, and improves gastro-duodenal coordination.
Rabeprazole is a PPI( Proton Pump Inhibitor) that suppresses gastric acid secretion by inhibiting H+/K+ ATPase at the secretory surface of the gastric parietal cell.
Indications
Chronic gastritis
GERD
Non ulcer dyspepsia
Dosage
ITORAX: 1 tab three times a day before meals
ITORAX RB: Once a day therapy before breakfast
Side Effects
Diarrhoea, constipation, abdominal pain, headache, sleeping disorders, dizziness, galactorrhea, gynecomastia
Contraindication
Hypersensitivity, lactation, GI haemorrhage, obstruction or perforation.
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