ITORAX RANGE

ITORAX- ITOPRIDE 50 MG TABLET
ITORAX- OD – ITOPRIDE 150MG SR
ITORAX-RB- ITOPRIDE (SR) 150MG +RABEPRAZOLE 20MG CAPSULE

Gastroenterology

ITORAX RANGE

ITORAX- ITOPRIDE 50 MG TABLET
ITORAX- OD – ITOPRIDE 150MG SR
ITORAX-RB- ITOPRIDE (SR) 150MG +RABEPRAZOLE 20MG CAPSULE

Gastroenterology

Indications

Chronic gastritis
GERD
Non ulcer dyspepsia

How it works

Itopride is a prokinetic benzamide derivative unlike metoclopramide or domperidone. These drugs inhibit dopamine and have a gastrokinetic effect. Itopride increases acetylcholine concentrations by inhibiting dopamine D2 receptors and acetylcholinesterase. Higher acetylcholine increases GI peristalsis, increases the lower esophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying, and improves gastro-duodenal coordination.
Rabeprazole is a PPI( Proton Pump Inhibitor) that suppresses gastric acid secretion by inhibiting H+/K+ ATPase at the secretory surface of the gastric parietal cell.

Indications

Chronic gastritis
GERD
Non ulcer dyspepsia

Dosage

ITORAX: 1 tab three times a day before meals
ITORAX RB: Once a day therapy before breakfast

Side Effects

Diarrhoea, constipation, abdominal pain, headache, sleeping disorders, dizziness, galactorrhea, gynecomastia

Contraindication

Hypersensitivity, lactation, GI haemorrhage, obstruction or perforation.

Technical information

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Gastroenterology

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