Diabetic Neuropathy
Fibromyalgia
Post-Herpetic Neuralgia
Low Back Pain
Post Operative Pain
Sciatica
Peripheral Neuropathy
How it works
Perfect duo to calm pain associated with neuropathy
How it works
Pregabalin, is an anticonvulsant drug used for neuropathic pain.It works by slowing down impulses in the brain that cause seizures. Pregabalin also affects chemicals in the brain that send pain signals across the nervous system.Pregabalin is a GABA analogue that binds to a subunit of voltage-gated calcium channels in CNS; does not affect sodium channels, opiate receptors, or cyclo-oxygenase enzyme activity; interactions with descending noradrenergic and serotonergic pathways originating from the brain stem appear to reduce neuropathic pain transmission from spinal cord
Nortriptyline is a tricyclic antidepressant. It affects chemicals in the brain that may be unbalanced in people with depression. Nortriptyline inhibits the reuptake of serotonin and norepinephrine by the presynaptic neuronal membrane, thereby increasing the concentration of these neurotransmitters in the synapse.
Indications
Diabetic Neuropathy
Fibromyalgia
Post-Herpetic Neuralgia
Low Back Pain
Post Operative Pain
Sciatica
Peripheral Neuropathy
Dosage
Once or Twice in a day
Side Effects
Common side effects associated are Dizziness, Sleepiness, Tiredness, Uncoordinated body movements
Contraindication
Contraindicated in pregnant and lactating women.
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