The newsletter for doctors

Cardio Nutshell Issue 2

March 30, 2022

The Cardio Nutshell Series 2 covers various sections. The first section discusses a case study that shows the effectiveness of mexiletine in shortening QT Interval in KCNH2-related long QT syndrome in a 23-year-old female with a history of recurrent syncopal episodes.

The next section of conference update covers “The Heart Failure 2021 and the World Congress on Acute Heart Failure” held between June 28th and July 1st, 2021. In this, Mareev Y et al suggested that patients with right ventricular pacing devices or new-onset atrial fibrillation have a particularly poor outcome as compared to those who remain in sinus rhythm. It was also suggested that atrial fibrillation may be an independent predictor of mortality in patients with heart failure and a reduced left ventricular ejection fraction.

The next section discusses the technological advancements in cardiology and the importance of wearable technology in healthcare with special focus on a stroke-detecting wristband that is currently under development.

This series concludes with the summary of a retrospective longitudinal study that appraises the long-term efficacy and safety of mexiletine in patients with myotonic dystrophy type 1. It concludes that mexiletine, at a dosage of 200 mg twice daily, appears to be safe in patients with DM1 and no severe conduction delay or severe ventricular dysfunction at baseline.

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