Neuropathy
Sleep disturbances
Male infertility
How it works
Methylcobalamin is the active form of vitamin B 12 i.e. cyanocobalamin which is used to prevent or treat disorders arising from the deficiency of vitamin B12, such as pernicious anemia.
MECHANISM
Like folic acid, methylcobalamin act as a methyl donor i.e. it transfer methyl group to another substance. Many important biochemical functions rely on this process of methylation, such as proper energy metabolism, immune and nerve functions. More specifically, methyl donors help in the production of several brain chemicals and hence improve cognitive functions, mood, energy and sleep. As body’s ability to methylate declines, it contributes to the process of ageing.
ROLE OF METHYLCOBALAMIN
Methylcobalamin is used in the treatment of peripheral neuropathy and diabetic neuropathy. It plays a vital role in the metabolism of fatty acids essential for the maintenance of nerve myelin. Prolonged B12 deficiency can lead to nerve degeneration and irreversible neurological damage. Methylcobalamin produces beneficial effects on somatosensory symptoms, such as pain and paresthesia (an abnormal sensation, typically tingling or pricking (‘pins and needles’), caused chiefly by pressure on or damage to peripheral nerves).
Also methycolamin causes a significant decrease in daytime melatonin levels while increasing nighttime levels which helps in improving sleep quality.
Indications
Neuropathy
Sleep disturbances
Male infertility
Dosage
1 Tablet OD.
Side Effects
Contraindication