DOFASMA OD: Doxofylline 650mg Modified Release Tablet
DOFASMA M: Doxofylline SR 400mg+Montelukast 10mg Tablet
DOFASMA A: Doxofylline 400mg+Ambroxol 30mg Tablet
DOFASMA OD: Doxofylline 650mg Modified Release Tablet
DOFASMA M: Doxofylline SR 400mg+Montelukast 10mg Tablet
DOFASMA A: Doxofylline 400mg+Ambroxol 30mg Tablet
COPD
Asthma
How it works
Doxofylline: It is a xanthine molecule having both Bronchodilator and Anti-inflammatory activity with an improved therapeutic window over conventional xanthines such as theophylline receptors, which may account for its better safety profile.
Ambroxol: It is a Mucolytic Agent that lowers the phlegm (mucus/sputum) viscosity and improves the mucociliary clearance mechanism of the respiratory tract. It stimulates synthesis and release of an Anti – Glue factor thus reduces the adhesion of mucus to the bronchial wall, improves its transport and provides protection against infection and irritating agents.
Montelukast :Belongs to Leukotriene Antagonist family. It work by blocking the production & action of Leukotriens. Thus reduces inflammation & nasal congestion.
Indications
COPD
Asthma
Dosage
Doxofylline Minimum and Maximum Dose:
Adult: 400mg once a day. Single dose, administration in the evening reduces nocturnal, symptoms and helps to keep the patients complaint free during the day. However, in certain cases, 400mg twice daily is recommended on the basis of the clinical response. Doses as high as 1200mg/day (400mg 3 times day) may also be prescribed.
Dofasma-A:
OD dose administration in the evening reduces nocturnal symptoms and helps to keep the patients complaint free during the day.
In certain cases BD dose is recommended on the basis of the clinical response.
Dofasma-M:
Preferably OD but can be given BD if required
Side Effects
Nausea or Vomiting
Stomach pain
Sleeplessness
Headache
Dizziness
Increased heartbeat
Increased blood sugar levels
Muscle weakness
Contraindication
Hypersensitivity to doxofylline, ambroxol, montelukast
Patients with acute myocardial infarction, hypotension and in breastfeeding women
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